Apigenin in Damiana Kills Breast Cancer Cells

Apigenin in Damiana, also known as Turnera diffusa, has been shown to kill breast cancer cells (MDA-MB-231) in vitro. Dr. Avelino-Flores and co-workers analyzed anticancer effect of extracts and organic fractions of Damiana plant on five tumor cell lines (SiHa, C-33, Hep G2, MDA-MB-231, and T-47D) and, also on normal human fibroblasts.

Four organic fractions of methanolic extract exhibited anticancer activity on MDA-MB-231 cancer cell line. And most active fraction was found to contain arbutin and apigenin. Here is the abstract of this recent study.

Products of Indonesian stingless bee kill human cancer cell lines

New research published in the “Asian Pacific Journal of Tropical Biomedicine”, showed propolis obtained from Indonesian stingless bees fight cancer cells, in vitro. Dr. Kustiawan PM  and co-workers stated the need of further studies to revealing the beneficial effects of bee products such as, propolis, bee pollen and royal jelly.

Combined apigenin and barasertib treatment can manage cetuximab resistance

Researchers from Laboratory of Cancer Research and Clinical Oncology, University of Antwerp, Belgium, showed that concomitant apigenin and barasertib treatment may overcome resistance to the cetuximab in head and neck cancers are squamous cell carcinomas (HNSCC). 

Apigenin protects neuronal injury in differentiated PC12 cells

Figure adapted from Wikipedia

Recent study, published in the Neurochemical Research at Sep 11, 2014, shows that apigenin may guard neuronal cells by virtue of its protective effects.

Dr. Huizhen Guo and colleagues found that apigenin attenuates oxygen and glucose deprivation/reperfusion (OGD/R) sitimulated neuronal injury mainly via antiapoptotic and antioxidative effects of apigenin.

Beer contains 47 polyphenols including apigenin

Researchers from the School of Pharmacy, University of Barcelona, showed that beer contains 47 phenolic compounds and 7 of them was identified for the first time including apigenin.